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Aging and the Immune System: the impact of immunosenescence on viral infection, immunity and vaccine immunogenicity

PMCID: PMC7653706

10.1016/j.jinorgbio.2007.06.020 49 FernndezR.BertrandA.GarcaJ

10.1016/j.tifs.2018.12.001 50 SuG.YangW.WangS.GengC.GuanX

Squalene supplementation enhances this process by increasing desmosterol levels, boosting LXR target gene expression, and facilitating cholesterol efflux from lipid-laden microglia (Gylling and Miettinen, 1994